This edition of ACTION — our twice annual publication highlighting our work in Innovation and Research — takes us back 20 years to the humble beginnings of our research team, when we began conducting our first clinical trial in oncology, made possible by the opening of the Grand River Regional Cancer Centre. In the last two decades, our capacity to expand our research and step into the world of health innovation has been made possible by our people: our patients, our passionate team members — which includes our staff, providers, volunteers, and students — who want to make care better for their patients, and our partners in our health, technology, and education systems. Our exciting partnership with local company, Hyivy Health, our first project of “patient-led” innovation, is an example of how we’re working with our community to improve care for our patients of today and the future. Additionally, being recognized as the Coordinated Accessible National (CAN) Health Network Edge of the Year, just three years after our partnership began, showcases not just the great work our team has done to date, but the potential we have to lead the way in transforming how we deliver health care.